A Structure Is Considered Irregular If It Exhibits Uneven Mass, Stiffness, And Strength Distributions Or Has An Irregular Shape. Most Structures Exhibit Irregularity For Functional And Aesthetic Reasons. One Significant Reason For A Structure’s Collapse During Past Earthquakes Is The Irregular Configuration Of The Structure, Either In Its Plan Or Elevation, As A Building’s Performance During A Seismic Event Is Largely Determined By Its Configuration. Therefore, Irregular Structures In Areas With High Seismic Activity Raise Significant Concerns. Structures May Have One Or More Types Of Structural Irregularities. Selecting The Type, Placement, And Extent Of Irregularities Is Vital In Structural Design. According To IS Code 1893 (Part 1): 2016, It Is Advisable To Minimize Irregularities By Updating Architectural Designs And Structural Layouts. The Idea Of “Perfect Regularity,” However, Is A Simplified Representation Since Real Buildings Always Have Irregularities Because Of Different Needs And Demands; These Irregularities Are Rather Common In Contemporary Urban Infrastructure. Structural Anomalies Have Thus Become Unavoidable, And This Work Attempts To Evaluate Their Performance. Lowering A Specific Percentage From The Standard (Square-Shaped) Reference Model, Results In Two L-Shaped Models With Plan Asymmetric And Two Setback Versions With Vertical Geometric Irregularities. A G+9 Storey Regular (Square-Shaped) RCC Frame Building Is Developed. Every Model Experiences Earthquake Load; Their Responses Are Computed With CSI ETABS Program. Response Spectrum Analysis Will Help Us To Reach The Goal By Comparing The Answers Of The Several Models.